Inhibition of GLI, but not Smoothened induces apoptosis in chronic lymphocytic leukemia cells.

Desch P, Asslaber D, Kern D, Schnidar H, Mangelberger D, Alinger B, Stoecher M, Hofbauer SW, Neureiter D, Tinhofer I, Aberger F, Hartmann TN, Greil R. Oncogene. 2010 Sep 2,29(35):4885-95. doi: 10.1038/onc.2010.243. Epub 2010 Jul 5.

Deletion of Puma and p21(Waf1) In Mice Deactivates p53-Induced Cell Death and Cell Cycle Arrest, but Protects Mice From Irradiation-Induced Lymphomagenesis by a Mechanism Involving Hemopoietic Stem Cell Quiescence

Hofbauer, JP, Holler, C, Denk, U, Asslaber, D, Fastner, G, Labi, V, Villunger, A, Greil, R, Egle, A BLOOD. 2010, 116(21): 45-46.

Enzastaurin kills human CLL cells regardless of clinical risk profile, but fails to prolong life in a murine CLL model

Kocher, T, Pinon, HJ, Holler, C, Denk, U, Greil, R, Egle, A ONKOLOGIE. 2010, 33: 40-40.

Final Analysis of Induction Treatment with Fludarabine, Cyclophosphamide Plus Rituximab (FCR) Followed by Fludarabine Plus Rituximab (FR) and Remission Maintenance Therapy with Rituximab In Previously Untreated B-Chronic Lymphocytic Leukemia (B-CLL): The Chairos AGMT CLL4/Roche ML18434 Study

Egle, A, Weiss, L, Melchardt, T, Gunsilius, E, Petzer, AL, Fridrik, M, Lang, A, Krieger, O, Thaler, J, Greil, R BLOOD. 2010, 116(21): 593-594.

Neue Therapie in Sicht.

Merkel O, Kenner L, Greil R SpringerMedizin. 22.09.2010

MicroRNAs as biomarkers for the diagnosis and prognosis of human cancer.

Asslaber D, Pinon Hofbauer J, Greil R, Egle A. Journal of Nucleic Acids Investigations. 2010, Dec 1, 1(1): 76-80.

Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia.

Merkel O, Asslaber D, PiГ±Гіn JD, Egle A, Greil R. Cell Cycle. 2010 Jul 15,9(14):2764-8. Epub 2010 Jul 3.

microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia.

Asslaber D, Piñón JD, Seyfried I, Desch P, Stöcher M, Tinhofer I, Egle A, Merkel O, Greil R. Blood. 2010 May 27,115(21):4191-7. doi: 10.1182/blood-2009-07-234823. Epub 2010 Jan 20.

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.

Merkel O, Hamacher F, Laimer D, Sifft E, Trajanoski Z, Scheideler M, Egger G, Hassler MR, Thallinger C, Schmatz A, Turner SD, Greil R, Kenner L. Proc Natl Acad Sci U S A. 2010 Sep 14,107(37):16228-33. doi: 10.1073/pnas.1009719107. Epub 2010 Aug 30.

Light chain-induced acute renal failure can be reversed by bortezomib-doxorubicin-dexamethasone in multiple myeloma: results of a phase II study.

Ludwig H, Adam Z, Hajek R, Greil R, TГіthovГЎ E, Keil F, Autzinger EM, Thaler J, Gisslinger H, Lang A, Egyed M, Womastek I, Zojer N. J Clin Oncol. 2010 Oct 20,28(30):4635-41. doi: 10.1200/JCO.2010.28.1238. Epub 2010 Sep 7.